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河南新县新型冠状病毒肺炎临床特点及诊断困难患者的诊疗策略 认领
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作者 冯博 金世宏 +1 位作者 李正兴 毛峥嵘 《中国医学工程》 2021年第2期6-12,共7页
目的分析河南新县11例新型冠状病毒肺炎患者的临床特点及诊断困难患者的诊疗策略,从而为全球疫情防控及临床诊疗提供依据。方法对2020年1月31日至2月26日期间在河南新县定点救治医院收治的11例新型冠状病毒肺炎患者的流行病学、临床表... 目的分析河南新县11例新型冠状病毒肺炎患者的临床特点及诊断困难患者的诊疗策略,从而为全球疫情防控及临床诊疗提供依据。方法对2020年1月31日至2月26日期间在河南新县定点救治医院收治的11例新型冠状病毒肺炎患者的流行病学、临床表现、诊断及治疗等情况进行梳理,并提出诊疗应对策略。结果11例患者中明确有直接或间接疫区接触史的9例,无明确疫区接触史者2例;聚集性发病者8例,非聚集性发病者3例。诊断依靠流行病学史、临床表现综合分析,最终经咽拭子核酸检测确诊,其中3例在诊断上具有一定难度。治疗上9例依据诊疗方案进行抗病毒治疗,2例应用新型抗病毒药物治疗。11例患者中1例危重型患者经治疗稳定后转上级医院进一步治疗,其余10例均治愈出院。结论综合患者的流行病学史、提高胸部影像学检查的诊断参考分量、扩大咽拭子核酸检测的普及面、加快新型确诊检测手段以及抗病毒药物的研发推广力度可能对目前全球疫情防控形势下新型冠状病毒肺炎患者的临床诊疗提供帮助。 展开更多
关键词 新型冠状病毒肺炎 临床特点 诊断 诊疗策略
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Chordoma Sociodemographic, Clinical and Therapeutic Aspects in National Institute of Oncology Rabat Morocco: A Report of 9 Cases 认领
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作者 Gaël Kietga Patricia Agbanglanon +3 位作者 Bertrand Compaore Evrard Seka Amine Lachgar Noureddine Benjaafar 《癌症治疗(英文)》 2021年第1期47-56,共10页
<strong>Introduction:</strong> <span><span><span style="font-family:""><span style="font-family:Verdana;">Chordoma is a rare bone tumor, which develops main... <strong>Introduction:</strong> <span><span><span style="font-family:""><span style="font-family:Verdana;">Chordoma is a rare bone tumor, which develops mainly from the sacrum, the base of the skull, or the spine. Surgery + radiotherapy (if necessary) is the standard treatment. Data on chordoma are scarce in this re</span><span style="font-family:Verdana;">gion, and thus, here we summarized 9 patients with this tumor whom we</span><span style="font-family:Verdana;"> treated in this institute. </span><b><span style="font-family:Verdana;">Material: </span></b><span style="font-family:Verdana;">Nine chordoma patients were summarized, who were treated in National Institute of Oncology in Rabat between 2013 </span><span style="font-family:Verdana;">and 2018. We retrieved data from medical charts and analyzed the clinical</span><span style="font-family:Verdana;"> characteristics of this tumor. </span><b><span style="font-family:Verdana;">Results: </span></b><span style="font-family:Verdana;">The average age was 49 years (range: 29 </span><span style="font-family:Verdana;">- 72), with male: female of 3:6. The manifestation-diagnosis time was 4</span><span style="font-family:Verdana;"> months (range: 2 - 14). Regarding the tumor location, lumbosacral spine;5, the skull;4. Mass was evident in 6. Signs of locoregional compressions (paraparesis or tetraparesis) were observed in 3. As for treatment, a partial tumor excision was performed in 8, with 3 patients undergoing a wide excision. Radiotherapy was done;3 patients with a dose of 46 Gy, 3 patients with 66 Gy, 1 patient with 50 Gy, and 1 patient with a 16 Gy gamma radio-knife in a single session. 4 patients with a dose of 46 Gy, 2 patients with 60 Gy, and 1 patient with a 16 Gy gamma radio-knife in a single session. Of 9, 4 patients had good locoregional control whereas 5 patients had local recurrence. </span><b><span style="font-family:Verdana;">Conclusion: </span></b><span style="font-family:Verdana;">Chordoma is a predominantly local aggressive tumor with low metastatic 展开更多
关键词 CHORDOMA Diagnosis Radiation Therapy Morocco
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Analysis on the Development Dilemma and Opportunity of Independent Clinical Laboratory Based on PEST-SWOT 认领
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作者 Wang Shuling Shi Ping 《亚洲社会药学》 2021年第1期31-40,共10页
Objective To study the current status of independent clinical laboratory(ICL)in China to offer some suggestions for further development of the industry because independent clinical testing is gradually occupying an im... Objective To study the current status of independent clinical laboratory(ICL)in China to offer some suggestions for further development of the industry because independent clinical testing is gradually occupying an important position in the medical market with the change of medical service mode.Methods The PEST-SWOT matrix model was constructed to sort out the strength and weakness,opportunities and threats of ICL and medical institutions.Results and Conclusion ICLs should enhance their social recognition by improving testing technology and industry operating standards.At the same time,it is also necessary to enhance their position in the clinical diagnosis industry and promote diversified competition in the field of clinical diagnosis so as to better help the development of national grading diagnosis and precision medicine.From the perspectives of SO,ST,WO,and WT,the development strategies of ICL are proposed,including personalized clinical diagnosis services and the construction of a database,and the family doctor system with community+ICL services.The remote diagnostic services should be implemented to help national graded diagnosis and treatment,and different operation schemes should be made to conform to market development.Besides,the access standards for ICL must be strictly required.Then,differentiated operations of enterprises should be valued for establishing industry brands and social awareness.Lastly,enterprises must focus on talents construction and management. 展开更多
关键词 independent clinical laboratory clinical diagnosis market clinical diagnosis institutions PESTSWOT matrix
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Pathogen Distribution and Laboratory Diagnosis of Acute Respiratory Infectious Diseases 认领
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作者 Zhiyong Qin Guosheng Su 《传染病进展(英文)》 2021年第1期21-28,共8页
<strong>Objective: </strong>To investigate the etiology distribution and laboratory diagnosis of acute respiratory infectious diseases. <strong>Methods:</strong> By searching, collecting and su... <strong>Objective: </strong>To investigate the etiology distribution and laboratory diagnosis of acute respiratory infectious diseases. <strong>Methods:</strong> By searching, collecting and summarizing the etiology distribution and laboratory diagnosis of respiratory infectious diseases, the latest research progress of acute respiratory infectious diseases was studied in order to provide reference for clinical prevention and treatment. <strong>Results:</strong> In the relevant literature collected, it is considered that acute respiratory infectious diseases refer to infectious diseases caused by pathogens invading human body from the nasal cavity, throat, trachea and bronchus. The main acute respiratory infectious diseases are SARS (acute severe respiratory syndrome), MERS (Middle East respiratory syndrome), 2019-ncov infection (new coronavirus pneumonia), pulmonary plague, influenza, measles, diphtheria, pertussis, rubella, meningitis, mumps, tuberculosis, etc. Different types of infection have different diagnostic methods, and different treatments are given according to different diseases. <strong>Conclusion:</strong> The etiology distribution and laboratory diagnosis of acute respiratory tract infectious diseases are understood through reference, which can provide better reference for clinical practice. Acute respiratory infectious disease is the most common clinical disease, which seriously endangers people’s health. 展开更多
关键词 Respiratory Infections PATHOGENS Clinical Diagnosis Prevention and Control Research
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原发性甲状腺淋巴瘤3例临床分析并文献复习 认领
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作者 柴春艳 张薇 +2 位作者 刘博 赵媛 徐邦强 《中国临床研究》 CAS 2021年第1期91-94,共4页
目的分析3例原发性甲状腺淋巴瘤患者的临床表现及诊治经过,并对原发性甲状腺淋巴瘤的诊疗进展进行文献复习。方法整理分析陕西省人民医院2017年至2019年收治的3例原发性甲状腺淋巴瘤患者的临床表现及诊治经过。结果3例原发性甲状腺淋巴... 目的分析3例原发性甲状腺淋巴瘤患者的临床表现及诊治经过,并对原发性甲状腺淋巴瘤的诊疗进展进行文献复习。方法整理分析陕西省人民医院2017年至2019年收治的3例原发性甲状腺淋巴瘤患者的临床表现及诊治经过。结果3例原发性甲状腺淋巴瘤患者临床表现均为无痛性甲状腺逐渐肿大,伴有不同程度的气道压迫症状,病理类型均为非霍奇金淋巴瘤弥漫大B细胞淋巴瘤。结论在甲状腺结节的诊断治疗中,应特别注意原发性甲状腺淋巴瘤的可能性,尤其是对既往患有桥本甲状腺炎的患者,更应提高警惕,其确诊需取得病理组织进行免疫组织化学检查。 展开更多
关键词 甲状腺肿瘤 淋巴瘤 诊断 鉴别诊断 免疫组织化学
经阴道三维超声检查对宫腔粘连的诊断价值及漏诊原因分析 认领
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作者 黄丽娜 何秀珍 《陕西医学杂志》 CAS 2021年第4期421-424,共4页
目的:探究经阴道三维超声(3D-TVS)检查对宫腔粘连的诊断价值及漏诊原因。方法:回顾性分析265例经宫腔镜及病理确诊为宫腔粘连患者资料,比较经阴道二维超声及3D-TVS诊断准确率、不同宫腔粘连粘连程度患者经3D-TVS扫描宫腔粘连子宫声像图... 目的:探究经阴道三维超声(3D-TVS)检查对宫腔粘连的诊断价值及漏诊原因。方法:回顾性分析265例经宫腔镜及病理确诊为宫腔粘连患者资料,比较经阴道二维超声及3D-TVS诊断准确率、不同宫腔粘连粘连程度患者经3D-TVS扫描宫腔粘连子宫声像图结果,并分析漏诊患者原因。结果:经3D-TVS诊断宫腔粘连总体准确率显著高于二维超声,并且对轻度宫腔粘连检出准确率明显优于二维超声(均P<0.05);3D-TVS与二维超声对中度、重度宫腔粘连检出准确率差异无统计学意义(均P>0.05)。应用二维超声将轻度宫腔粘连漏诊为正常宫腔57例(21.51%);3D-TVS漏诊10例(3.77%),两种检查方法漏诊率比较差异有统计学意义(P<0.05)。结论:经3D-TVS检查,可直观显示出宫腔粘连患者粘连程度及分型,可结合患者临床表现进行有效诊断,同时需注意易引起漏诊的因素,以提高诊断准确率。 展开更多
关键词 经阴道三维超声 经阴道二维超声 宫腔粘连 诊断 漏诊
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Adenoid Cystic Carcinoma Invade the Tracheal Prominence: A Case Report and Literature Review 认领
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作者 Kaiwen He Haitao Huang +2 位作者 Shaomu Chen Yu Feng Haitao Ma 《临床医学病理报告(英文)》 2021年第1期8-16,共9页
<strong>Background: </strong>Adenoid cystic carcinoma (ACC) refers to a salivary gland neoplasm. Tracheal adenoid cystic carcinoma that invades the tracheal prominence is a relatively rare tumor among thor... <strong>Background: </strong>Adenoid cystic carcinoma (ACC) refers to a salivary gland neoplasm. Tracheal adenoid cystic carcinoma that invades the tracheal prominence is a relatively rare tumor among thoracic diseases.<strong> Objective: </strong>To explore the epidemiology, diagnosis, treatment and future development of tracheal adenoid cystic carcinoma (TACC). <strong>Methods:</strong> With asymptomatic invasion of the tracheal prominence, a case of tracheal adenoid cystic carcinoma with asymptomatic invasion of the tracheal prominence was reported. The clinical management process and surgical methods were introduced, and related literature was reviewed and summarized. <strong>Results: </strong>The patient was admitted due to tracheal augmentation mass for half a month. Chest CT at admission displayed the soft tissue density shadow behind the tracheal augmentation process. After the completion of other examinations, tracheal tumor resection and tracheal reconstruction were performed. Postoperative routine pathology exhibited that it was TACC and without inguinal lymph node metastasis. <strong>Conclusion:</strong> TACC is a low-grade tracheal tumor with low incidence, delayed clinical manifestations and lack of specificity as well. CT and bronchoscopy are helpful for the diagnosis of suspected patients. Meanwhile, radical surgical resection is the first choice of treatment. Adjuvant therapy can improve the therapeutic effect. Targeted immunotherapy is the developing direction of treatment. 展开更多
关键词 Tracheal Adenoid Cystic Carcinoma DIAGNOSIS TREATMENT
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Inquiry Based on Evidence and its Practices in Two Healthcare Facilities of Bujumbura 认领
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作者 Emmanuel Gasaba Jean Paul Nshimiyimana +6 位作者 Le Beni Bugingo Ismaël Twiyubare Marie Jeanine Ndayishimiye Jonathan Niciza Emmanuel Ndarusanze Clovis Ntahondahurira Edouard Niyongabo 《护理学期刊(英文)》 2021年第3期170-183,共14页
<strong>Background:</strong> Inquiry evidence-based practice (IBP) improves healthcare quality, reliability, and patient outcomes as well as reduces variations in care and costs. IBP and its practice in he... <strong>Background:</strong> Inquiry evidence-based practice (IBP) improves healthcare quality, reliability, and patient outcomes as well as reduces variations in care and costs. IBP and its practice in health care promote also many advantages, such as improvements of practices based on the attitudes and cognitive ideas. This study aims to assess the inquiry based on evidence (IBP) and its practices in two Health Care Facilities (HCFs) of Bujumbura to help the practitioners to understand its importance. <strong>Methods:</strong> A cross-sectional study design was used to analyze the importance of IBP and its practice in these two hospitals. The probability-sampling technique was used also to select 104 nurses from the Military Hospital of Kamenge and 55 nurses from the Van Norman Clinic. A questionnaire was used to collect data with two mains components, demographic data and knowledge and attitudes addressing the following parameters: evidence practice during inquiry, nursing theory, current analysis in nursing care oriented the evidence, prioritization of care, rational diagnostic, monitoring and assessment. <strong>Results:</strong> The findings from this study revealed a poor knowledge and attitude among participants towards Inquiry Based Practice. In all variables, participants were scoring less than 10%. However, majority of participants (76.5%) know the indicators of patients’ satisfaction with nursing interventions through survey-based practice and 74.1% argued to analyze their information collected. <strong>Conclusion:</strong> This study revealed a weak awareness on IBP and its importance during nursing practice among participants as for almost all variables, participants were scoring less than 10%, except for the indicators of patients’ satisfaction with nursing interventions through survey-based practice (76.5%). Therefore, in-service training and curriculum revision had been highlighted and recommended another to provide the best rational diagnosis and achieve the patient’s outcomes. 展开更多
关键词 Inquiry Evidence-Based Practice Evidence-Based Practice Healthcare Facilities Rational Diagnosis
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Improving CAD Hemorrhage Detection in Capsule Endoscopy 认领
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作者 Polydorou Alexios Sergaki Eleftheria +4 位作者 Polydorou Andreas Barbagiannis Christos Vardiambasis Ioannis George Giakos Zervakis Michail 《生物医学工程(英文)》 2021年第3期103-118,共16页
This study explores an automated framework to assist the recognition of hemorrhage traces and bleeding lesions in video streams of small bowel capsule endoscopy (SBCE). The proposed methodology aims to achieve fast im... This study explores an automated framework to assist the recognition of hemorrhage traces and bleeding lesions in video streams of small bowel capsule endoscopy (SBCE). The proposed methodology aims to achieve fast image control (<10 minutes), save valuable time of the physicians, and enable high performance diagnosis. A specialized elimination algorithm excludes all identical consecutive frames by utilizing the difference of gray levels in pixel luminance. An image filtering algorithm is proposed based on an experimentally calculated bleeding index and blood-color chart, which inspects all remaining frames of the footage and identifies pixels that reflect active or potential hemorrhage in color. The bleeding index and blood-color chart are estimated of the chromatic thresholds in RGB and HSV color spaces, and have been extracted after experimenting with more than 3200 training images, derived from 99 videos of a pool of 138 patients. The dataset has been provided by a team of expert gastroenterologist surgeons, who have also evaluated the results. The proposed algorithms are tested on a set of more than 1000 selected frame samples from the entire 39 testing videos, to a prevalence of 50% pathologic frames (balanced dataset). The frame elimination of identical and consecutive frames achieved a reduction of 36% of total frames. The best statistical performance for diagnosis of positive pathological frames from a video stream is achieved by utilizing masks in the HSV color model, with sensitivity up to 99%, precision 94.41% to a prevalence of 50%, accuracy up to 96.1%, FNR 1%, FPR 6.8%. The estimated blood-color chart will be clinically validated and used in feature extraction schemes supporting machine learning ML algorithms to improve the localization potential. 展开更多
关键词 Capsule Endoscopy Small Bowel Bleeding Detection Computer Aided Diagnosis (CAD) Color Models Color Feature
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Prenatal Diagnosis and Management of Fetal Goiter Treated Successfully with Intra-Amniotic Levothyroxine 认领
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作者 Valentina Corda Cristina Peddes +1 位作者 Ambra Iuculano Giovanni Monni 《妇产科期刊(英文)》 2021年第1期48-52,共5页
Goiter is an enlargement of the thyroid gland which can be associated with a number of complications both for the mother and the fetus. A 34-year-old pregnant woman with normal thyroid function was referred to our Dep... Goiter is an enlargement of the thyroid gland which can be associated with a number of complications both for the mother and the fetus. A 34-year-old pregnant woman with normal thyroid function was referred to our Department of Obstetrics and Gynecology at Microcitemico Pediatric Hospital, Cagliari, for suspected fetal goiter at 32 gestational weeks. The case was monitored regularly by ultrasound and treated successfully with intra-amniotic levothyroxine (L-T4) administration. Fetal goiter was observed to decrease after this treatment and the thyroid ultrasound findings were also normal both at birth and in subsequent follow-ups. Our case report confirms the feasibility of conservative treatment with L-T4, which can effectively prevent complications related to fetal goiter. 展开更多
关键词 Fetal Goiter Prenatal Diagnosis Prenatal Therapy AMNIOCENTESIS Fetal Thyroid Fetal Ultrasound Levothyroxine (L-T4)
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咳嗽的全科诊断策略 认领
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作者 陈凯 梁翠菲 《中国全科医学》 CAS 北大核心 2021年第13期1707-1710,1716,共5页
咳嗽是全科的常见主诉,其病因广泛,同时也可能是某些危重疾病的潜在信号,对全科医生来说,咳嗽的诊断是一个时刻面临的挑战。本文从全科医生的角度,对咳嗽的病因进行分析和总结,并结合相关文献和指南,梳理出咳嗽的诊断思路,通过病史采集... 咳嗽是全科的常见主诉,其病因广泛,同时也可能是某些危重疾病的潜在信号,对全科医生来说,咳嗽的诊断是一个时刻面临的挑战。本文从全科医生的角度,对咳嗽的病因进行分析和总结,并结合相关文献和指南,梳理出咳嗽的诊断思路,通过病史采集、体格检查、诊断性检查及治疗正确评估病情,以帮助全科医生在临床实践中及时、准确地诊断咳嗽,避免严重后果,最终达到提高患者治疗效果、构建和谐医患关系的目的。 展开更多
关键词 咳嗽 全科医学 诊断 鉴别诊断
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Intelligent Information Management in Aquaponics to Increase Mutual Benefits 认领
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作者 Divas Karimanzira Cai Na +1 位作者 Mu Hong Yaoguang Wei 《智能信息管理(英文)》 2021年第1期50-69,共20页
Aquaponics are feedback and two player systems, in which fish and crops mutually benefit from one another and, therefore require close monitoring, management and control. Vast amount of data and information flow from ... Aquaponics are feedback and two player systems, in which fish and crops mutually benefit from one another and, therefore require close monitoring, management and control. Vast amount of data and information flow from the aquaponics plant itself with its huge amount of smart sensors for water quality, fish and plant growth, system state etc. and from the stakeholder, e.g., farmers, retailers and end consumers. The intelligent management of aquaponics is only possible if this data and information are managed and used in an intelligent way. Therefore, the main focus of this paper is to introduce an intelligent information management (IIM) for aquaponics. It will be shown how the information can be used to create services such as predictive analytics, system optimization and anomaly detection to improve the aquaponics system. The results show that the system enabled full traceability and transparency in the aquaponics processes (customers can follow what is going on at the farm), reduced water and energy use and increased revenue through early fault detection. In this, paper the information management approach will be introduced and the key benefits of the digitized aquaponics system will be given. 展开更多
关键词 Intelligent Information Management Double Recirculation Aquaponic System DIGITIZATION Monitoring and Remote Diagnosis System Optimization
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原发性肝脏弥漫性大B细胞淋巴瘤1例MDT讨论 认领
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作者 黄阳 李先泰 +4 位作者 易成 郑金利 蒲星宇 蒋利 严律南 《中国普外基础与临床杂志》 CAS 2021年第2期236-242,共7页
目的总结1例原发性肝脏弥漫性大B细胞淋巴瘤(primary diffuse large B cell lymphoma of liver,PDLBCLL)的临床表现和影像学表现,并探讨其病因、组织来源、病理特点、诊断和鉴别诊断、治疗方法的选择及预后,以提高对该病的认识及合理诊... 目的总结1例原发性肝脏弥漫性大B细胞淋巴瘤(primary diffuse large B cell lymphoma of liver,PDLBCLL)的临床表现和影像学表现,并探讨其病因、组织来源、病理特点、诊断和鉴别诊断、治疗方法的选择及预后,以提高对该病的认识及合理诊治水平。方法回顾性分析四川大学华西医院于2019年6月诊治的1例PDLBCLL患者的临床病理学资料。结果PDLBCL术前诊断极为困难,与原发性肝癌等肝占位性病变难以鉴别,且容易忽略淋巴造血组织肿瘤侵犯肝脏可能,往往经过术后病理诊断或穿刺活检提示、且经各项检查排除血液系统疾病后才得以明确诊断。该例患者以右肝占位收入院,术前影像学检查考虑为肿瘤可能,经MDT讨论后认为:先由肝脏外科手术切除明确肿瘤性质后,再于肿瘤科就诊。遂行不规则右半肝切除术+胆囊切除术+肝门淋巴结清除术+膈肌修补术,术后病理学检查结果诊断为PDLBCLL。手术持续时间约为230 min,术中出血约200 mL。患者术后恢复可,无并发症发生,于术后第10天出院。已门诊随访9个月,每月定期复查肝肾功、电解质等指标及腹部彩超检查,结果均未见明显异常。结论PDLBCLL的治疗方式多样,目前暂无统一的治疗原则,多为手术、化疗、放疗或联合治疗。目前,由于其病因不明,机制不清,临床医生只能根据患者病情特点实施个体化治疗。 展开更多
关键词 原发性肝脏弥漫性大B细胞淋巴瘤 诊断 鉴别诊断 MDT讨论 治疗
琥珀酸脱氢酶缺陷型肾细胞癌的临床病理特征 认领
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作者 王桃丽 曹云 陈栋良 《临床与病理杂志》 2021年第1期233-239,共7页
运用HE染色及免疫组织化学(immunohistochemistry,IHC)等方法分析3例琥珀酸脱氢酶缺陷型肾细胞癌(succinate dehydrogenase-deficient renal cell carcinoma,SDH-deficient RCC)的临床病理特征、免疫表型,并结合相关文献进行综合分析。... 运用HE染色及免疫组织化学(immunohistochemistry,IHC)等方法分析3例琥珀酸脱氢酶缺陷型肾细胞癌(succinate dehydrogenase-deficient renal cell carcinoma,SDH-deficient RCC)的临床病理特征、免疫表型,并结合相关文献进行综合分析。在3例SDH缺陷型肾细胞癌患者中,男女均有发生,年龄22~48(平均39.33)岁,病变位于左肾1例,右肾2例。其中1例患者发生同一侧肾脏肿块2个,分别位于右肾上极和右肾下极。所有肿瘤大体边界清楚,无明确包膜,边缘呈推挤性生长,切面实性,均质,灰红或灰褐色。镜下观:肿瘤组织结构多样,呈巢状、小管状、腺泡状或实性结构,肿瘤细胞呈多边形或圆形,细胞界限不清楚,细胞质丰富,嗜酸性或透明,细胞质内可见空泡状或包涵体结构,并可见嗜酸性絮状物,细胞核圆形或卵圆形,核膜光滑规则,染色质细腻,核仁不明显,细胞核大小较一致,为低级别核;肿瘤周边可见正常肾小管或肾小球。IHC显示SDH亚单位B(SDHB)抗体表达缺失,肿块周边非肿瘤组织,包括肾小管、血管内皮细胞及炎症细胞均呈阳性表达。3例患者手术治疗后随访2~8个月,均存活。SDH缺陷型肾细胞癌具有典型的病理组织学细胞特征,确诊需要IHC标记证实。 展开更多
关键词 肾细胞癌 SDH缺陷 诊断 鉴别诊断 免疫组织化学
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全面腹部超声检查诊断急腹症的临床效果 认领
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作者 谌兰 《中国继续医学教育》 2021年第7期116-119,共4页
目的评定全面腹部超声检查方法使用于急腹症患者诊断过程中所得到的临床诊断效果。方法对2018年6月—2020年2月本医院诊断的74例急腹症患者实施这次具体数据资料分析,针对各个组别予以随机抽签方式分组,不同组别纳入例数依次37例,试验... 目的评定全面腹部超声检查方法使用于急腹症患者诊断过程中所得到的临床诊断效果。方法对2018年6月—2020年2月本医院诊断的74例急腹症患者实施这次具体数据资料分析,针对各个组别予以随机抽签方式分组,不同组别纳入例数依次37例,试验组运用全面腹部超声检查方法,参照组运用传统腹部超声检查方法,评价各个组别超声检查所用时长、临床诊断所用时长、临床诊断符合总计数值。结果试验组超声检查所用时长、临床诊断所用时长相比参照组降低(P<0.05);试验组临床诊断符合总计数值相比对参照组提升(P<0.05)。结论在急腹症患者诊断过程中采取全面腹部超声检查方法得到良好临床诊断效果。 展开更多
关键词 全面腹部超声检查 诊断 急腹症 影像 超声检查所用时长 临床诊断所用时长
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超声新技术用于乳腺增生症诊断的临床进展 认领
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作者 房婧 《中国医疗器械信息》 2021年第3期39-40,共2页
乳腺增生症是临床常见的妇女疾病,发病率较高。其主要症状是乳腺上皮与纤维组织出现增生,患者乳房会出现疼痛、乳房肿块等问题。若不及时治疗,容易导致肿块出现癌变。因此,临床早期诊断病情对疾病的治疗有重要意义。以往临床均是应用黑... 乳腺增生症是临床常见的妇女疾病,发病率较高。其主要症状是乳腺上皮与纤维组织出现增生,患者乳房会出现疼痛、乳房肿块等问题。若不及时治疗,容易导致肿块出现癌变。因此,临床早期诊断病情对疾病的治疗有重要意义。以往临床均是应用黑白B超展开诊断,但是特异性不强,检查结果存在一定的局限性,逐渐被彩色多普勒所替代。超声诊断是比较简单、直接的方式,具有实时动态的优点,可清晰反映出病变的形态与大小。彩超只是诊断技术中应用较多的一种,除此之外还有包括三维超声、超声弹性成像等技术。为进一步了解超声技术在乳腺增生中的应用,综述近年来的相关诊断技术,研究其临床进展。 展开更多
关键词 超声新技术 乳腺增生症 诊断 临床进展
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血栓弹力图联合D-二聚体在肺部手术后下肢深静脉血栓形成的预测价值 认领
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作者 虞亚菲 张海平 +1 位作者 居来提·艾尼瓦尔 朱辉 《中国血管外科杂志:电子版》 2021年第1期38-41,共4页
目的探讨血栓弹力图(thrombelastography,TEG)联合D-二聚体在预测患者肺部手术后下肢深静脉血栓形成(deep vein thrombosis,DVT)的临床价值。方法选取2019年6~12月新疆医科大学第一附属医院行胸腔镜下肺部手术98例患者作为研究对象,根... 目的探讨血栓弹力图(thrombelastography,TEG)联合D-二聚体在预测患者肺部手术后下肢深静脉血栓形成(deep vein thrombosis,DVT)的临床价值。方法选取2019年6~12月新疆医科大学第一附属医院行胸腔镜下肺部手术98例患者作为研究对象,根据发生DVT情况分为DVT组(15例)和非DVT组(83例)。比较两组的TEG指标和D-二聚体水平,绘制受试者工作特征(receiver operating characteristic,ROC)曲线,并计算TEG指标及D-二聚体在DVT的诊断效能。结果TEG MA值是患者发生DVT的独立预测因素(OR=4.660,95%CI=1.578~13.758,P=0.005)。ROC曲线显示,TEG R值、K值、α角、MA值和D-二聚体在预测DVT形成的曲线下面积分别为0.831(95%CI=0.067~0.271)、0.878(95%CI=0.792~0.964)、0.847(95%CI=0.739~0.954)、0.983(95%CI=0.963~1.000)和0.823(95%CI=0.699~0.947),最佳截断值分别为5.05 min、1.25 min、70.5°、70.1 mm和0.66 mg/L。TEG联合D-二聚体诊断的准确率、灵敏度、阳性预测值明显高于TEG和D-二聚体单独诊断。结论TEG能有效预测肺部术后发生DVT的风险,TEG联合D-二聚体在预测DVT发生具有较高诊断价值。 展开更多
关键词 血栓弹力图 D-二聚体 肺部手术 深静脉血栓形成 诊断
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小儿巨大腹主动脉旁副神经节瘤报道1例 认领
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作者 侯永川 吴克刚 +4 位作者 欧阳辰昕 邓琳 刘瑜 周柯均 王城 《中外医学研究》 2021年第1期167-169,共3页
目的:探讨腹主动脉旁副神经节瘤临床特点及诊治思路。方法:对1例腹主动脉旁副神经节瘤患儿病例资料进行分析,并进行文献复习。结果:患儿以高血压为主要临床表现,影像学检查提示腹膜后占位;手术切除术后,病检为副神经节瘤。结论:副神经... 目的:探讨腹主动脉旁副神经节瘤临床特点及诊治思路。方法:对1例腹主动脉旁副神经节瘤患儿病例资料进行分析,并进行文献复习。结果:患儿以高血压为主要临床表现,影像学检查提示腹膜后占位;手术切除术后,病检为副神经节瘤。结论:副神经节瘤以手术切除为主要治疗方式,术前充分扩容,控制血压,术中减少挤压,尽可能保证瘤体包膜完整,是手术成功的关键;长期随访也是不可缺少的环节。 展开更多
关键词 副神经节瘤 诊断 治疗
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外周血液中循环肿瘤细胞和循环游离DNA检测在乳腺癌患者中的应用 认领
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作者 樊霞 付景林 刘静 《诊断病理学杂志》 2021年第1期47-50,54,共5页
目的探究外周血液中循环肿瘤细胞(CTCs)和循环游离DNA(cfDNA)检测在乳腺癌患者中的应用效果。方法收集本院2018-02—2019-02收治的94例乳腺癌患者、48例乳腺良性疾病患者及56例健康体检者外周血液标本,采用基于尺寸的高通量微流控芯片捕... 目的探究外周血液中循环肿瘤细胞(CTCs)和循环游离DNA(cfDNA)检测在乳腺癌患者中的应用效果。方法收集本院2018-02—2019-02收治的94例乳腺癌患者、48例乳腺良性疾病患者及56例健康体检者外周血液标本,采用基于尺寸的高通量微流控芯片捕获CTCs、基于Alu序列的实时荧光定量PCR检测游离DNA长、短片段(247 bp、115 bp),并以长、短片段扩增产物比值作为DNA完整性指标。分析CTCs和cfDNA与乳腺癌临床参数的关系,并评估其在乳腺癌诊断中的作用。结果乳腺癌患者在CTCs、血浆cfDNA的基于Alu序列的Alu 247/115的比值上显著比健康体检者、乳腺良性疾病者高(P<0.05),乳腺癌患者外周血中CTCs的数量与血浆cfDNA的基于Alu序列的Alu 247/115的比值在年龄、病理分期、淋巴结转移、分子分型、远处转移、PR有一定的相关性(P<0.05),以病理学结果作为金标准,以约登指数最大点对应的临界值,以乳腺良性疾病患者和健康体检者作对照,当CTCs cut-off值为7.68个/ml,灵敏度为80.4%,特异度为96.4%,ROC曲线下面积为0.885(95%CI 0.805~0.965);Alu 247/115的cut-off值为0.431时,特异度为71.4%,ROC曲线下面积为0.727(95%CI 0.608~0.847),灵敏度为71.7%。结论 CTCs与cfDNA可能是乳腺癌辅助诊断的潜在生物学指标,CTCs检测的是肿瘤细胞,cfDNA检测的是肿瘤的DNA片段,可作为判断乳腺癌患者的病情变化和诊断的良好辅助指标,此方法值得应用与推广。 展开更多
关键词 乳腺癌 循环肿瘤细胞 循环游离DNA 诊断
星座链球菌致面部脓肿的诊断学特征并文献复习 认领
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作者 李小龙 宋江勤 +3 位作者 丁妍 周君阳 胡晓蓉 欧阳娟 《中华诊断学电子杂志》 2021年第1期13-16,共4页
目的探讨星座链球菌致面部脓肿的诊断学特征。方法回顾性分析2020年6月27日天门市第一人民医院肿瘤科收治的1例星座链球菌致面部脓肿患者的临床资料,并文献复习。结果患者临床表现为右颌面部肿块,肿块部分皮肤破溃,且有脓性分泌物流出;... 目的探讨星座链球菌致面部脓肿的诊断学特征。方法回顾性分析2020年6月27日天门市第一人民医院肿瘤科收治的1例星座链球菌致面部脓肿患者的临床资料,并文献复习。结果患者临床表现为右颌面部肿块,肿块部分皮肤破溃,且有脓性分泌物流出;既往有鼻咽癌病史。影像学提示右侧中耳乳突炎、鼻窦炎;实验室检查:人类疱疹病毒IgA抗体为弱阳性,C-反应蛋白11.07 mg/L,降钙素原1.26μg/L。血培养阴性,伤口分泌物检出星座链球菌,对红霉素、克林霉素耐药。结论星座链球菌作为一种机会致病菌,可引起人体各组织器官发生化脓性感染,应引起临床重视并提高病原菌的检出率,做到早诊断、早治疗。 展开更多
关键词 链球菌 星座 细菌感染 面部脓肿 诊断
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